Focused on understanding the intricate relationship between metabolism and health, research in metabolic medicine is crucial. At Blood Genius, we are actively involved in clinical research that includes ground-breaking research in cholesterol management – the results of which led to the rolling out of injectable cholesterol medicines. Dr Mbagaya is a national chief investigator, principal investigator and sub-investigator in a number of clinical trials.

As early adopters of technology in medicine, we are better able to understand the underlying mechanisms of metabolic disorders and the new therapies to target them. This enables us to identify new risk factors, biomarkers and genetic mutations associated with metabolic disorders.

As advocates of personalised and patient-led medicine, we also believe that teaching and training is important for several reasons:

Patient education

Patients with metabolic and cardiometabolic disorders require education on their condition, including its causes, symptoms, treatments and the lifestyle changes that may be recommended. Our team are trained, knowledgeable and effective in communicating this information to patients. We provide corporate teaching on metabolic health and cardiometabolic diseases.

Prevention

Metabolic disorders such as diabetes, obesity and heart disease are largely preventable through lifestyle changes such as diet and exercise. By teaching patients about healthy lifestyle habits, we can help prevent the onset or progression of these disorders.

Treatment

Effective treatment of metabolic disorders often involves a combination of medications, diet and exercise. We are knowledgeable about the latest treatment options and strategies to provide optimal care to our patients.

Best practice

Regular training helps our physicians and other healthcare professionals keep up-to-date with the latest research, guidelines and best practices in metabolic medicine. Training also helps us to understand the importance of early detection and prevention of metabolic disorders. With early detection, our patients can receive timely interventions to prevent the progression of a disease and reduce the risk of complications.

We believe that research and training in metabolic medicine are essential for improving patient outcomes and reducing the burden of metabolic disorders.

Teaching

Dr Mbagaya has extensive teaching experience as an honorary senior lecturer at University of Bristol Medical School. He teaches GPs nationally on cardiometabolic medicine, lipidology and laboratory medicine. He also supports companies and patient groups in health education.

Publications

Jassam N, Bancroft T, Luvai A, Mbagaya W, Barth JH. Vitamin B12 reference intervals on Beckman, Roche and Siemens analytical platforms. Ann Clin Biochem. 2023;0(0). doi:10.1177/00045632231202211

Mbagaya W, Luvai A, Waise A. Diagnostic biochemical markers for heart failure. Pract Diab 2018: 35; 149-151

Barth JH, Luvai A., Jassam N, Mbagaya W, Kilpatrick ES, Narayanan D, Spoors S. Comparison of method-related reference intervals for thyroid hormones: studies from a prospective reference population and a literature review. Ann Clin Biochem 2017: 55;107-112

Mbagaya W, Luvai A, Lopez B. Biological variation of troponin in stable haemodialysis patients. Ann Clin Biochem 2015: 52;562-568

Luvai A, Mbagaya W, Narayanan D, Degg T, Toogood G, Wyatt JI, Swinson D, Hall CJ, Barth JH. Hepatocellular carcinoma in variegate porphyria: a case report and literature review. Ann Clin Biochem 2015: 52;407-412

Jassam N, Mbagaya W, Kallner A, Hill R, Carless D, Barth JH, Delaney, H, Lippiatt C, Shepherd J, Glover S, Slack S, Mitchell K, Strafen A, Bosomworth MP. Does creatinine analytical performance support robust identification of acute kidney injury within individual laboratories in a region? Clin Chem Lab Med 2015: 53; e63-e65

Mbagaya W, Orme SM. Weight Loss and Dizziness: Adrenal Failure. In R. Ajjan, S.M. Orme (eds.), Endocrinology and Diabetes: Case Studies, Questions and Commentaries © Springer-Verlag London 2015. pp 91 -97

Mbagaya W, Foo J, Luvai A, King C, Mapplebeck S, Gough A, Jassam N. Persistently raised aspartate aminotransferase (AST) due to macro-AST in a rheumatology clinic. Diagnosis. 2015: 2;137-140, ISSN (Online) 2194-802X, ISSN DOI: 10.1515/dx-2014-0065, January 2015

Narayanan D, Mbagaya W, Aye M, Kilpatrick ES, Barth JH. Management of severe in-patient hyponatraemia: an audit in two teaching hospitals in Yorkshire, UK. Scand J Clin Lab Invest 2015: 75;1-6

Luvai A, Mbagaya W, Hall AS, Barth JH. Rosuvastatin: A Review of the Pharmacology and Clinical Effectiveness in Cardiovascular Disease. Clinical Medicine Insights: Cardiology 2012: 6; 17-33

Luvai A. Mbagaya W. Patient Management: Secondary Hyperlipidaemia. Foundation Years Journal. 2011:5; 40-43

Abstracts And Posters

Graby J, Sellek J, Bayly G, Avades T, Capps N, Shipman K,  Mbagaya W, et al, 174 Ct coronary angiography significantly changes treatment targets versus coronary artery calcium scoring in high-risk dyslipidaemia patients Heart 2022;108:A135-A136

Powers, V. Mbagaya, W. Stockdale, C. Dawson, C (2016) Hyperammonaemia secondary to chemotherapy: unmasking and exacerbation of underlying urea cycle defects in two patients. J Inherit Metab Dis vol 39 pp S61

Mbagaya, W. Narayanan, D. Poon, P. Kilpatrick, ES (2011) The effect of the introduction of a high sensitivity troponin T assay on the prevalence of myocardial infarction in 2 Yorkshire hospitals. Annals of Clinical Biochemistry vol 48 pp S23. Shortlisted for Siemens prize

Mbagaya, W. Barth, JH (2011) Hyperlipidaemia as an initial presentation of myeloma. Atherosclerosis vol 218, Issue 2, pp e6-7

Narayanan D, Aye, M. Mbagaya, W (2009) Survey of aetiology, investigations and outcome of severe hyponatraemia in in-patients. Annals of Clinical Biochemistry vol 46 pp S27

Narayanan, D. Mbagaya, W. Barth, J (2009) Reproducibility of the short synacthen test. Annals of Clinical Biochemistry vol 46 pp S74

Ali, M. Mbagaya, W. Andrews, J. Orme, S (2009) False-positive Dexamethasone Suppression Test following use of rifampicin in a male patient. Endocrine Abstracts vol 21 pp56

If you have any questions or would like to book an appointment, please contact us today.